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Publication Date

2-17-2026

Description

Abstract Body:

Objectives: This review aims to examine the overall effects of e-cigarettes on oral health, including its associations with xerostomia, dental caries, periodontal disease, and oral cancer.

Methods: A systematic review was conducted using databases like PubMed, ScienceDirect, NIH, and MDPI, analyzing many studies published between 2010-2025. Inclusion criteria consisted of peer-reviewed human and in-vitro studies that evaluated the oral effects of e-cigarettes. Studies were screened for correlation to caries formation, salivary changes, mucosal alterations, microbiome disruptions, and carcinogenic potential.

Results: A total of fifteen studies were included. Findings across studies showed that e-cigarettes reduce salivary flow rates and alters pH, leading to xerostomia and increased bacterial colonization. E-cigarette aerosols were found to elevate oxidative stress, upregulate proinflammatory cytokines, and impair gingival fibroblast function, thereby accelerating periodontal tissue destruction. Additionally, vapor condensates containing formaldehyde and acrolein have been linked to DNA damage and epithelial dysplasia. Chronis use was further associated with delayed wound healing and altered perception.

Conclusion: E-cigarettes pose significant risks to oral health, contributing to increased rates of xerostomia, caries, periodontal inflammation and potentially oral cancer. Dental professionals should recognize e-cigarettes as an emerging public health concern and integrate both patient education and screening into preventative care. Longitudinal studies are warranted to determine the long-term oncogenic effects and establish evidence-based clinical guidelines for management and prevention.

Disciplines

Dental Public Health and Education

Keywords

"E-cigarette", "oral health", "caries", "oral cancer", "periodontal", "electronic nicotine delivery system"

Document Type

Poster

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The Impact of E-cigarettes: A Review of Risks and Emerging Evidence

Abstract Body:

Objectives: This review aims to examine the overall effects of e-cigarettes on oral health, including its associations with xerostomia, dental caries, periodontal disease, and oral cancer.

Methods: A systematic review was conducted using databases like PubMed, ScienceDirect, NIH, and MDPI, analyzing many studies published between 2010-2025. Inclusion criteria consisted of peer-reviewed human and in-vitro studies that evaluated the oral effects of e-cigarettes. Studies were screened for correlation to caries formation, salivary changes, mucosal alterations, microbiome disruptions, and carcinogenic potential.

Results: A total of fifteen studies were included. Findings across studies showed that e-cigarettes reduce salivary flow rates and alters pH, leading to xerostomia and increased bacterial colonization. E-cigarette aerosols were found to elevate oxidative stress, upregulate proinflammatory cytokines, and impair gingival fibroblast function, thereby accelerating periodontal tissue destruction. Additionally, vapor condensates containing formaldehyde and acrolein have been linked to DNA damage and epithelial dysplasia. Chronis use was further associated with delayed wound healing and altered perception.

Conclusion: E-cigarettes pose significant risks to oral health, contributing to increased rates of xerostomia, caries, periodontal inflammation and potentially oral cancer. Dental professionals should recognize e-cigarettes as an emerging public health concern and integrate both patient education and screening into preventative care. Longitudinal studies are warranted to determine the long-term oncogenic effects and establish evidence-based clinical guidelines for management and prevention.