The Ninth Chondroid Syringoma with Bone Formation: A Case Report

Authors

Mojan Deriss, Roseman University of Health SciencesFollow
Kelsey Ouyang, Cleveland Clinic Lerner Research InstituteFollow
Parnian Alizadeh, Harvard UniversityFollow
Amir Qorbani, University of California, San FranciscoFollow
Voicu S. Ciobanu, Roseman University of Health Sciences

Publication Date

2-18-2026

Description

This poster presents a rare case of chondroid syringoma with ossification, representing only the ninth reported instance of bone formation within this adnexal tumor. The report describes a slowly enlarging facial nodule in a 34-year-old male, detailing clinical presentation, surgical excision, and histopathologic findings. Microscopy revealed characteristic epithelial cords and tubules within a myxoid stroma, along with mature lamellar bone formation, confirming the diagnosis. The case expands the known morphologic spectrum of chondroid syringomas and highlights the importance of considering this entity in the differential diagnosis of benign facial masses, particularly when unusual features such as ossification are present.

Disciplines

Neoplasms | Skin and Connective Tissue Diseases

Keywords

Chondroid Syringoma, Chondroid syringoma with Bone formation, chondroid syringoma with ossification, Mixed tumor of the skin, Adnexal tumor, Bone formation, Ossification, Mixed tumor of the skin, Histopathology, Myxoid stroma, Ectopic bone, Osteoid differentiation, Case report

Document Type

Poster

Recommended Citation

Deriss, Mojan; Ouyang, Kelsey; Alizadeh, Parnian; Qorbani, Amir; and Ciobanu, Voicu S., "The Ninth Chondroid Syringoma with Bone Formation: A Case Report" (2026). Annual Research Symposium. 11.
https://ecommons.roseman.edu/researchsymposium/2026/clinical/11